Interaction betweenHelicobacter pyloriand host genetic variants in gastric carcinogenesis
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چکیده
منابع مشابه
Genetic Instability in Nuclear and Mitochondrial DNAs during Gastric Carcinogenesis
Gastric cancer (GC) is highly prevalent in Asia and the third most common cause of cancer death after lung cancer and liver cancer in Korea (Jung et al., 2012). The 5-year survival rate for gastric cancer is over 60%, however, the late onset of clinical symptoms occurred late diagnose at an advanced stage, which limits available therapeutic approaches in more than 50% of cases (Strong et al., 2...
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background hepatitis b virus (hbv) infection is a serious public health problem in china and worldwide. mother-to-child transmission is one of hbv’s main transmission routes in highly endemic regions. genome-wide association studies (gwas) identify single nucleotide polymorphisms (snps) at hla loci as associated with hbv infection. however, the mechanisms of hbv perinatal transmission and break...
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Currently, gastric adenocarcinoma is still a serious healthcare concern, and the second most frequent malignancy worldwide (1). Although overall incidence has seemingly decreased, both its frequency and mortality rate show relevant geographic variability. In Eastern countries, Eastern Europe, and South America the incidence of this disease reaches epidemic proportions, and is the first cause of...
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Subgroup J avian leukosis virus (ALV-J), a typical retrovirus, is characterized of existence of a cloud of diverse variants and considerable genetic diversity. Previous studies describing the evolutionary dynamics of ALV-J genetic variants mainly focused on the early infection period or few randomly selected clones. Here, we inoculated 30 specific-pathogen-free chickens with the same founder AL...
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Direct-acting antiviral drugs (DAAs) are currently replacing antiviral therapy for Hepatitis C infection. Treatment related side effects are even worse and the emergence of resistant viruses must be avoided because of the direct-antiviral action. Altogether it remains a challenge to take treatment decisions in a clinical setting with cost restrictions. Genetic host factors are hereby essential ...
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ژورنال
عنوان ژورنال: Future Oncology
سال: 2016
ISSN: 1479-6694,1744-8301
DOI: 10.2217/fon-2016-0233